KEGG   Ovis aries (sheep): 808251
Entry
808251            CDS       T03117                                 
Symbol
COX1
Name
(RefSeq) cytochrome c oxidase subunit I
  KO
K02256  cytochrome c oxidase subunit 1 [EC:7.1.1.9]
Organism
oas  Ovis aries (sheep)
Pathway
oas00190  Oxidative phosphorylation
oas01100  Metabolic pathways
oas04260  Cardiac muscle contraction
oas04714  Thermogenesis
oas04932  Non-alcoholic fatty liver disease
oas05010  Alzheimer disease
oas05012  Parkinson disease
oas05014  Amyotrophic lateral sclerosis
oas05016  Huntington disease
oas05020  Prion disease
oas05022  Pathways of neurodegeneration - multiple diseases
oas05208  Chemical carcinogenesis - reactive oxygen species
oas05415  Diabetic cardiomyopathy
Module
oas_M00154  Cytochrome c oxidase
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    808251 (COX1)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    808251 (COX1)
  09159 Environmental adaptation
   04714 Thermogenesis
    808251 (COX1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    808251 (COX1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    808251 (COX1)
   05012 Parkinson disease
    808251 (COX1)
   05014 Amyotrophic lateral sclerosis
    808251 (COX1)
   05016 Huntington disease
    808251 (COX1)
   05020 Prion disease
    808251 (COX1)
   05022 Pathways of neurodegeneration - multiple diseases
    808251 (COX1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    808251 (COX1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    808251 (COX1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:oas03029]
    808251 (COX1)
Enzymes [BR:oas01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.9  cytochrome-c oxidase
     808251 (COX1)
Mitochondrial biogenesis [BR:oas03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Cytochrome c oxidase
    808251 (COX1)
SSDB
Motif
Pfam: COX1
Other DBs
NCBI-GeneID: 808251
NCBI-ProteinID: NP_008408
UniProt: O78749 Q5MA75
Structure
Position
MT:5332..6876
AA seq 514 aa
MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTA
HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA
GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQ
TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH
PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD
TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLAN
SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVG
VNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMIFIIWEAFASKR
EVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
NT seq 1545 nt   +upstreamnt  +downstreamnt
atgttcatcaaccgctgattattttcaaccaaccacaaagatatcggcaccctttacctt
ctatttggtgcctgagctggtatagtaggaaccgccttaagcctactaattcgcgccgaa
ctaggccaacccggaactctactcggagatgaccaaatctacaacgtaattgtaaccgca
catgcatttgtaataattttctttatagtaatgcctattataatcggtggattcggcaac
tgactagttcctctgataattggagcccctgatatagcatttcctcggataaataacata
agcttttgacttcttcccccatctttcctgttactcctagcatcctctatggttgaggcc
ggagcaggaacaggttgaaccgtataccctcctctagcaggcaacctagcccatgcagga
gcctcagtagatctaactattttctccctacatctggcaggtgtctcttcaattctagga
gccattaattttattacaactattattaatataaaaccccctgcgatgtcacagtatcaa
acccccttgtttgtatgatctgtactaattactgccgtacttctccttctctcacttcct
gtattagcagctggtatcacaatactactaacggaccgaaacctgaatacaacctttttt
gacccagcaggaggaggagaccctatcctatatcaacacctattctgattctttgggcac
cctgaagtatatattcttattttacctgggtttgggataatctcccatattgtgacctac
tattcaggaaaaaaagaaccattcggatatataggaatagtatgagccataatatcaatt
gggttcctaggattcattgtatgagcccaccatatattcacagtcggaatagacgtcgat
acacgggcttacttcacgtcagctactataattatcgccatcccaacaggagtaaaagta
ttcagttgactagcaacgcttcatgggggtaatatcaaatgatctcctgccataatatga
gccctaggtttcatctttcttttcacagtcggaggcttaactggaattgttctagccaac
tcctcccttgacattgtcctccatgacacatattatgtagtagcacatttccactacgta
ttatcaataggagctgtatttgctattataggaggatttgtacattgatttcccctattc
tcaggctatactctcaatgatacatgagccaaaatccactttgcaattatatttgtaggt
gttaacatgactttctttccacagcatttcctaggactatccggtataccacgacgatac
tctgattatccagacgcatatacaatatgaaatactatctcatctataggctcatttatc
tcactaacagcagtaatactaataatcttcatcatctgagaagcatttgcatctaaacga
gaagtcctaactgtagacctaaccacaacaaacctagaatgactaaacggatgtcctcca
ccataccacacatttgaagaacccacatatgttaacctaaaataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (14)   
   KEGG PATHWAY (13)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (30)   

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